Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers for Judith Reichmann

(Goethe University Frankfurt) The formation of gametes and the first cell divisions of the fertilized egg in mammals are prone to errors. Sometimes the wrong number of chromosomes is passed on to the offspring, or the first division leads to two nuclei instead of one in the two-cell embryo. In most cases, these errors result in miscarriages. Judith Reichmann has shown what leads to these errors in mouse embryos.